20. Courteney Cox
Courteney Cox had already made a couple of seasons of Friends when the first Scream film came out, and that was nearly held against her. How? Well, Cox wasn’t initially seen as a viable choice for the part of reporter Gale Weathers given her reputation for playing nicer characters. Still, she eventually won through – and made it to the end of the series to date. Cox, of course, played Monica Gellar on Friends until its last episode in 2004; she’s also had considerable TV success with Cougar Town.